Study Overview
In skin, fibroblasts are found primarily in the dermis and produce collagen type I, which gives skin elasticity, and hyaluronic acid, which moisturizes. Fibroblast cells are important in terms of beauty, as a decline in their function can lead to wrinkles and sagging.
This study will verify the fibroblast-activating effect of the test substance by measuring the production levels of collagen type I and hyaluronic acid, with the aim of verifying and searching for new functional substances that provide firmness and moisture to the skin.
Study example
Compound C promotes collagen production.
Basic Experimental design
| Cells used | Normal human dermal fibroblasts |
|---|---|
| Positive control | Vitamin C (ascorbic acid), etc. |
| Preliminary study | Cytotoxicity assay |
| Main study | Cell proliferation rate measurement Collagen type I and hyaluronic acid production measurement |
*Studies will be mainly conducted by those with doctoral degrees.
