Study Overview
We uses the Keyence BZ-X700 fluorescence microscope to observe and image many different kinds of samples. Using this microscope, we offer services related to fluorescence imaging and sample observation for our customers. Beyond simple observation, we offer comprehensive cell-based testing services that span the whole study process, including cell cultivation, substance application, and fluorescence microscope analysis.
Equipment used

BZ-X700 (KEYENCE)
Features of the BZ-X700
The Keyence BZ-X700 is an all-in-one fluorescence microscope that integrates the functionality of a confocal microscope, slide scanner, and live-cell incubator into a single platform. Featuring a built-in darkroom and a high-sensitivity cooled CCD camera, it enables high-resolution imaging in fluorescence, brightfield, and phase contrast while reducing photobleaching. Its automated system streamlines research by offering advanced capabilities such as seamless XYZ stitching of large tissue sections, Z-stacking for 3D modeling, and real-time quantification, allowing researchers to obtain accurate, publication-quality data significantly faster than with traditional microscopes.

Resolving fluorescence blur
- Haze reduction (removal of fluorescence blur)
- Sectioning (laser-less, clear, blur-free images)

Advanced analysis possible
- Full focus
- 3D analysis
- Quantification
- Time lapse (observation of changes over time)
- High-resolution image stitching
Analysis example 1: Three-dimensional analysis (is GFP expressed on the cell membrane or translocated to the nucleus?)
Analysis example 2: Three-dimensional analysis (sperm)
Resistant to fading and minimizes damage
- High-sensitivity monochrome/color switchable cooled CCD
- Fade reduction mode
Ease of operation
- Fully motorized control
- Large motorized stage
- Stage view
- Navigation
- Autofocus (Instant focus ⇒ Limited bleaching of fluorescence)
- Real-time overlay (Adjusting the exposure while overlaying multiple channels in real time allows for composite images to be generated)


Brightfield observation possible
- High-sensitivity monochrome⇔color switchable cooled CCD
*Studies will be mainly conducted by those with doctoral degrees.

