Study Overview
Collagenase belongs to a family of proteins called matrix metalloproteinase (MMP), and is an enzyme that breaks down collagen. Excessive collagenase activity in the skin leads to a reduction of collagen levels, leading to wrinkles and skin sagging. Substances that are capable of inhibiting collagenase activity are expected to be of use for cosmetic applications.
Additionally, in the field of oncology, collagenase is associated with the process of cancer metastasis. Substances that are able to inhibit collagenase activity may also find use in the field of oncology as an anti-metastatic drug.
In this study, various collegenases are used to evaluate if test substances are able to inhibit collagenase activity.
Study example
Basic Experimental design
| Cells used | None (in vitro study) |
|---|---|
| Measurement items | Collagenase activity measurement (fluorescence method) using various collagenases (MMPs) |
*All our studies are mainly performed and handled by our team of PhD scientists.
