Study Overview
Collagenase (MMP) is an enzyme that breaks down collagen, and it is known that excessive collagen activity in the skin leads to a decrease in collagen levels, resulting in wrinkles and sagging. Therefore, substances that inhibit enzyme activity are expected to be useful in cosmetic applications.
Furthermore, in the field of cancer, collagenase is activated when cancer metastasizes, so substances that inhibit enzyme activity may also be useful in suppressing cancer metastasis.
In this study, various collagenases will be used to verify the collagenase inhibitory effects of the test substances.
Study example
Basic Experimental design
| Cells used | None (in vitro study) |
|---|---|
| Measurement items | Collagenase activity measurement (fluorescence method) using various collagenases (MMPs) |
*Studies will be mainly conducted by those with doctoral degrees.
