Study Overview
Thrombosis, which can lead to strokes and heart attacks, occurs when blood clots obstruct blood flow. Antithrombotic factors such as PGI2, NO, eNOS, and thrombomodulin are able to improve thrombosis by possessing vasodilatory properties. This study determines if a test substance has the ability to prevent blood clots through exerting antithrombotic and vasodilatory effects.
Study example
Basic Experimental design
| Cells used | Normal human umbilical vein endothelial cells (HUVEC), HAoEC, etc. |
|---|---|
| Preliminary study | Cytotoxicity assay |
| Main study | Prostacyclin production measurement NO production measurement Thrombomodulin, eNOS gene expression analysis, etc. |
*All our studies are mainly performed and handled by our team of PhD scientists.
