Study Overview
This study aims to verify and search for substances that have an effect on improving neurodegenerative diseases, including Alzheimer’s disease, by using neurons to verify the neurite outgrowth-promoting activity of the test substance, as well as its protective effect against amyloid beta and oxidative stress. We conduct the study using high-content screening equipment that enables high-speed cell-based imaging analysis, allowing for highly accurate and high-throughput analysis.
Study example
Basic Experimental design
| Cells used | PC-12, SH-SY5Y, etc. |
|---|---|
| Preliminary study | Cytotoxicity assay |
| Main study | Neurite outgrowth activity assessment Hydrogen peroxide (H2O2) and amyloid beta toxicity avoidance assessment Dopamine production measurement |
*Studies will be mainly conducted by those with doctoral degrees.
